Human Lactate Dehydrogenase A Inhibitor Screening Kit (Colorimetric)
供应商
Biovision
产品货号
K492-100
产品报价
¥询价/100assays
产品说明书
购买方式
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产品新闻
背景资料
待更新
产品描述
The human oxidoreductase Lactate Dehydrogenase A (LDHA) (EC:1.1.1.27) is a key enzyme in lactic acid metabolism. It interconverts pyruvate and NADH to lactate and NAD+ respectively. In mammals, LDHA exists as a tetramer and is primarily found in skeletal muscle tissues. LDHA is a common marker to assay for tissue damage and is also known to promote tumor proliferation in breast, lung, and pancreatic cancer patients. In BioVision’s LDHA Inhibitor Screening Kit, LDHA catalyzes the conversion of lactate to an intermediate that interacts with a probe to develop a color that can be measured at OD 450 nm. In the presence of a LDHA specific inhibitor, the reaction is impeded. A LDHA Inhibitor Control is included to compare the efficacy of the sample inhibitors. The assay is high-throughput adaptable and can be completed in less than 1 hr
产品特点
• Simple and sensitive assay.
Fast protocol - can be performed in 30 min.
HTP adaptable.