Human Thioredoxin 1 (Trx1) Inhibitor Screening Kit (Fluorometric)
供应商
Biovision
产品货号
K535-100
产品报价
¥询价/100assays
产品说明书
购买方式
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产品新闻
背景资料
待更新
产品描述
The human Thioredoxin 1 (Trx1) is a key enzyme that protects cells from oxidative stress by reducing disulfides and methionine sulfoxide groups in oxidized proteins. It also regulates DNA repair and apoptosis. In mammals, Trx1 is necessary for growth and development. However, an aberrant elevated expression of Trx1 is known to promote lung, cervical, pancreatic, colorectal, and breast cancers. In BioVision’s Trx1 Inhibitor Screening Kit, Trx1 reduces quenched di-FITC-labeled oxidized glutathione (Trx1 substrate), to mono-FITC-labeled unquenched reduced glutathione. In the presence of a Trx1 inhibitor (control inhibitor included), the reaction is impeded resulting in lower or no signal. The assay is high-throughput adaptable and can be completed in less than 1 hr
产品特点
• Rapid, simple & sensitive
• Convenient & HTS
• Includes inhibitor control