Rabbit IgG polyclonal antibody for Aldehyde dehydrogenase family 1 member A3(ALDH1A3) detection. Tested with WB, IHC, IHC-F, ICC/IF, FCM in Human;Mouse;Rat.
英文名字
Rabbit IgG polyclonal antibody for Aldehyde dehydrogenase family 1 member A3(ALDH1A3) detection. Tested with WB, IHC, IHC-F, ICC/IF, FCM in Human;Mouse;Rat.
Aldehyde dehydrogenase 1 family, member A3, also known as ALDH1A3 or retinaldehyde dehydrogenase 3 (RALDH3), is an enzyme that in humans is encoded by the ALDH1A3 gene. Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or a cellular retinol-binding protein form. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants.
应用类型
FC,ICC,IF,IHC,WB
免疫原
E.coli-derived human ALDH1A3 recombinant protein (Position: N37-K154). Human ALDH1A3 shares 89% and 87.3% amino acid (aa) sequence identity with mouse and rat ALDH1A3, respectively.