Rabbit IgG polyclonal antibody for Cadherin-1(CDH1) detection. Tested with WB, IHC, IHC-F, IF, ELISA in Human;Mouse;Rat.-Rabbit IgG polyclonal antibody for Cadherin-1(CDH1) detection. Tested with WB, IHC, IHC-F, IF, ELISA in Human;Mouse;Rat.代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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中文名称: Rabbit IgG polyclonal antibody for Cadherin-1(CDH1) detection. Tested with WB, IHC, IHC-F, IF, ELISA in Human;Mouse;Rat.

英文名字: Rabbit IgG polyclonal antibody for Cadherin-1(CDH1) detection. Tested with WB, IHC, IHC-F, IF, ELISA in Human;Mouse;Rat.

背景资料: CDH1 (Cadherin 1), also known as ECAD or UVO, is a protein that in humans is encoded by the CDH1 gene. Cadherin-1 is a classical member of the cadherin superfamily. By Southern analysis of DNA from a panel of mouse-human somatic cell hybrids, Mansouri et al. (1987, 1988) assigned the UVO gene to 16q (16p11-qter). Frebourg et al. (2006) found that in human embryos CDH1 is highly expressed at 4 and 5 weeks in the frontonasal prominence and at 6 weeks in the lateral and medial nasal prominences, and is therefore expressed during critical stages of lip and palate development. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.

免疫原: E.coli-derived human E Cadherin recombinant protein (Position: A286-A703). Human E Cadherin shares 79.7% and 80.9% amino acid (aa) sequence identity with mouse and rat E Cadherin, respectively.

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