用于ATP1B1检测的兔IgG多克隆抗体。采用WB、IHC、ICC/IF、FCM、直接ELISA检测人体;小鼠;大鼠-Rabbit IgG polyclonal antibody for ATP1B1 detection. Tested with WB, IHC, ICC/IF, FCM, Direct ELISA in Human;Mouse;Rat.代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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英文名字: Rabbit IgG polyclonal antibody for ATP1B1 detection. Tested with WB, IHC, ICC/IF, FCM, Direct ELISA in Human;Mouse;Rat.

背景资料: Sodium/potassium-transporting ATPase subunit beta-1 is an enzyme that in humans is encoded by the ATP1B1 gene. The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.

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