Rabbit IgG polyclonal antibody for Beta-arrestin-1(ARRB1) detection. Tested with WB, IHC in Human;Mouse;Rat.-Rabbit IgG polyclonal antibody for Beta-arrestin-1(ARRB1) detection. Tested with WB, IHC in Human;Mouse;Rat.代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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中文名称: Rabbit IgG polyclonal antibody for Beta-arrestin-1(ARRB1) detection. Tested with WB, IHC in Human;Mouse;Rat.

英文名字: Rabbit IgG polyclonal antibody for Beta-arrestin-1(ARRB1) detection. Tested with WB, IHC in Human;Mouse;Rat.

背景资料: Arrestin, beta 1, also known as ARRB1, is a protein which in humans is encoded by the ARRB1 gene. Members of arrestin/beta-arrestin protein family are though to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. By fluorescence in situ hybridization, this gene is mapped to 11q13.4. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase(BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.

免疫原: A synthetic peptide corresponding to a sequence at the N-terminus of human beta Arrestin 1(82-103aa ANVQSFPPAPEDKKPLTRLQER), identical to the related rat and mouse sequences.

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