用于14 - 3 - 3蛋白σ（SFN）检测的兔IgG多克隆抗体。用WB、IHC、ICC、ICC/IF、FCM检测人体;小鼠;大鼠-Rabbit IgG polyclonal antibody for 14-3-3 protein sigma(SFN) detection. Tested with WB, IHC, ICC, ICC/IF, FCM in Human;Mouse;Rat.代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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英文名字: Rabbit IgG polyclonal antibody for 14-3-3 protein sigma(SFN) detection. Tested with WB, IHC, ICC, ICC/IF, FCM in Human;Mouse;Rat.

背景资料: Stratifin(SFN), also known as 14-3-3 protein sigma, is strongly induced by gamma irradiation and other DNA-damaging agents. The induction of 14-3-3-sigma is mediated by a p53 -responsive element located 1.8 kb upstream of its transcription start site. Leffers et al.(1993)obtained peptide sequence and subsequently cloned a T-cell cDNA of the 14-3-3 family of conserved proteins. The protein, called stratifin, was shown to be diffusely distributed in the cytoplasm and was present in cultured epithelial cells. It was most abundant in tissues enriched in stratified keratinizing epithelium.

免疫原: A synthetic peptide corresponding to a sequence in the middle region of human 14-3-3 sigma(140-156aa KKRIIDSARSAYQEAMD), identical to the related rat and mouse sequences.

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