CD54 (ICAM-1) is a member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation. _x000D_
应用类型
FC,IP,WB,IHC,ICC,FA
免疫原
Mouse NS-1 cells_x000D_
来源宿主
该Rabbit IgG polyclonal antibody for CD45/Ptprc detection. Tested with WB, IHC, Direct ELISA in Mouse;Rat.产品的来源宿主详情查看产品说明书。