用于开发夹心ELISA试剂盒，以测定细胞培养上清液、细胞裂解物、血清和血浆（肝素、EDTA）中的人瘦素。-For the development of sandwich ELISA kit to measure human Leptin in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).代理/参数/厂家-ELISA试剂盒-开云·官方站线上登录平台入口

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ELISA试剂盒

开云·官方站线上登录平台入口_开云(中国)

英文名字: For the development of sandwich ELISA kit to measure human Leptin in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

背景资料: Leptin(or obese, OB) is a circulating hormone that is expressed abundantly and specifically in the adipose tissue. Human ob protein is a 166-amino acid polypeptide with a putative signal sequence and is 84 and 83% homologous to the mouse and rat ob proteins, respectively. Northern blot analysis reveals that OB RNA is present at a high level in adipose tissue but at much lower levels in placenta and heart. Indeed, Leptin is first described as an adipocyte-derived signalling factor, which, after interaction with its receptors, induces a complex response including control of bodyweight and energy expenditure. Leptin seems in addition to its role in metabolic control to have important roles in reproduction and neuroendocrine signalling. Leptin is a powerful inhibitor of bone formation in vivo. Comparative mapping of mouse and human DNA indicates that the ob gene is located within a region of mouse chromosome 6 that is homologous to a portion of human chromosome 7q. The standard product used in this kit is recombinant human Leptin.

产品描述: 瘦素（或肥胖，OB）是一种循环激素，在脂肪组织中大量特异性表达。人ob蛋白是一种166个氨基酸的多肽，具有推定的信号序列，与小鼠和大鼠ob蛋白分别有84%和83%的同源性。北方印迹分析显示，OB RNA在脂肪组织中的表达水平较高，但在胎盘和心脏中的表达水平较低。事实上，瘦素首先被描述为脂肪细胞衍生的信号传导因子，其在与其受体相互作用后，诱导包括控制体重和能量消耗的复杂反应。瘦素似乎除了在代谢控制中的作用外，在生殖和神经内分泌信号传导中也有重要作用。瘦素是体内骨形成的强效抑制剂。小鼠和人DNA的比较作图表明ob基因位于小鼠6号染色体的一个区域内，该区域与人7号染色体的一部分同源。本试剂盒使用的标准品为重组人瘦素。

其他: Nordic BioSite(北欧生物) 总部位于瑞典，成立于1997年，旨在分销研究和诊断领域的高质量和创新产品。 Nordic BioSite 被公认为整个北欧生物医学研究和诊断产品领域的领导者。他们拥有超过570万种的产品组合，代理了遍布欧洲和美国的顶级生物试剂制造商，是欧洲知名的一站式生物试剂代理商。除了作为分销商之外，Nordic BioSite 还拥有不断增长的自产产品线——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自产产品线(共26W+产品)。Nordic BioSite的产品类型主要是抗体，蛋白和试剂盒，产品适用范围涵盖15个不同的物种(人，牛，犬，鲶鱼，鸡，海豚，马，猫，豚鼠，小鼠，绵羊，兔子，大鼠，猪和火鸡)，可为您提供一站式的生命科学研究解决方案~