Human CellExp™ Integrin alpha V beta 5 Heterodimer, Human recombinant
供应商
Biovision
产品货号
P1121-50
产品报价
¥已停产
产品说明书
购买方式
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产品新闻
背景资料
Integrin alpha V beta 5 (ITGAV & ITGB5 or ITGAVB5) is expressed on a wide variety of cell types including keratinocytes, fibroblasts, adhesive monocytes, embryonic stem cells, and select endothelium and epithelium. ITGAV & ITGB5 binds ligands containing an RGD motif, notably vitronectin. Growth factors that increase PKC activity, such as VEGF or TGF alpha, promote ITGAVB5-mediated angiogenesis while alpha V beta 3, which may be expressed in the same cell, responds to FGF-basic and TNF alpha. An inhibitor of both down regulates tumor angiogenesis. During lung inflammation, up regulation of ITGAVB5 on myofibroblasts or infiltrating lymphocytes may contribute to fibrosis by freeing TGF beta from latency.
序列
提供的Human CellExp™整合素αV beta 5异二聚体,人类重组Human CellExp™ Integrin alpha V beta 5 Heterodimer, Human recombinant是Biovision品牌中国区域总代理艾美捷科技产品,具体的蛋白序列可查看提供的英文版本产品说明书。
来源宿主
提供的Human CellExp™整合素αV beta 5异二聚体,人类重组Human CellExp™ Integrin alpha V beta 5 Heterodimer, Human recombinant产品来源宿主,查看该产品说明书,或者在线咨询我们。
溶解建议
Reconstitute in sterile deionized water to the desired protein concentration.