Human CellExp™ Gremlin / GREM1, Fc Tag, Human recombinant
供应商
Biovision
产品货号
P1123-10
产品报价
¥已停产
产品说明书
购买方式
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产品新闻
背景资料
Gremlin is also known as Cysteine knot superfamily 1, BMP antagonist 1 (CKTSF1B1), DAN domain family member 2 (DAND2), Down-regulated in Mos-transformed cells protein (DRM), Increased in high glucose protein 2 (IHG-2), Cell proliferation-inducing gene 2 protein (PIG2) or Gremlin-1 (GREM1), which is highly expressed in small intestine, fetal brain and colon. Gremlin / GREM-1 interacts with SLIT1 and SLIT2 in a glycosylation-dependent manner. Gremlin may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Gremlin down-regulates the BMP4 signaling in a dose-dependent manner and acts as inhibitor of monocyte chemotaxis.
序列
提供的Human CellExp™Gremlin / GREM1,Fc标签,人类重组Human CellExp™ Gremlin / GREM1, Fc Tag, Human recombinant是Biovision品牌中国区域总代理艾美捷科技产品,具体的蛋白序列可查看提供的英文版本产品说明书。
来源宿主
提供的Human CellExp™Gremlin / GREM1,Fc标签,人类重组Human CellExp™ Gremlin / GREM1, Fc Tag, Human recombinant产品来源宿主,查看该产品说明书,或者在线咨询我们。
溶解建议
Reconstitute in sterile deionized water to the desired protein concentration.