Human CellExp™ RAGE / AGER, Fc Tag, Human Recombinant
供应商
Biovision
产品货号
P1231-50
产品报价
¥已停产
产品说明书
购买方式
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产品新闻
背景资料
Advanced glycosylation end product-specific receptor (AGER) is also known as RAGE, and is a single-pass type I membrane protein which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. AGER is highly expressed in endothelial cells. AGER mediates interactions of advanced glycosylation end products (AGE), and also accumulates in vascular tissue in aging and at an accelerated rate in diabetes, as well as acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGER / RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes.
序列
提供的Human CellExp™愤怒/ AGER,Fc标签,人类重组Human CellExp™ RAGE / AGER, Fc Tag, Human Recombinant是Biovision品牌中国区域总代理艾美捷科技产品,具体的蛋白序列可查看提供的英文版本产品说明书。
来源宿主
提供的Human CellExp™愤怒/ AGER,Fc标签,人类重组Human CellExp™ RAGE / AGER, Fc Tag, Human Recombinant产品来源宿主,查看该产品说明书,或者在线咨询我们。
溶解建议
Reconstitute in sterile deionized water to the desired protein concentration.