INS, also known as insulin preproprotein, is a biologically inactive precursor to the biologically active endocrine hormone insulin. Insulin is an essential hormone for maintaining metabolic homeostasis in the body. To make fully bioactive insulin, pancreatic beta cells initiate synthesis of INS. It is converted into proinsulin by signal peptidases, which remove its signal peptide from its N-terminus. Finally, proinsulin is converted into the bioactive hormone insulin by removal of the C-peptide. Recombinant human INS, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography techniques.
序列
提供的INS,25-110 aa,His-tag,人类重组INS, 25-110 aa, His-tag, Human Recombinant是Biovision品牌中国区域总代理艾美捷科技产品,具体的蛋白序列可查看提供的英文版本产品说明书。
来源宿主
提供的INS,25-110 aa,His-tag,人类重组INS, 25-110 aa, His-tag, Human Recombinant产品来源宿主,查看该产品说明书,或者在线咨询我们。
溶解建议
该INS,25-110 aa,His-tag,人类重组INS, 25-110 aa, His-tag, Human Recombinant产品的溶解建议详情请查阅产品说明书。