Human CellExp™ CD33 / SIGLEC-3, Fc Tag, Human Recombinant
供应商
Biovision
产品货号
P1334-50
产品报价
¥已停产
产品说明书
购买方式
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产品新闻
背景资料
Myeloid cell surface antigen CD33 also known as SIGLEC3, Siglecs (sialic acid binding Ig-like lectins) and GP67, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Human CD33 / Siglec-3 cDNA encodes a 364 amino acid (aa) polypeptide with a hydrophobic signal peptide, an N--terminal Ig--like V--type domain, one Ig--like C2--type domains, a transmembrane region and a cytoplasmic tail. CD33 / Siglec-3 usually considered myeloid-specific, but it can also be found on some lymphoid cells. In the immune response, CD33 / Siglec-3 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 Domain (s) that block signal transduction through dephosphorylation of signaling molecules. CD33 / Siglec-3 induces apoptosis in acute myeloid leukemia.
序列
提供的Human CellExp™CD33 / SIGLEC-3,Fc标签,人类重组Human CellExp™ CD33 / SIGLEC-3, Fc Tag, Human Recombinant
是Biovision品牌中国区域总代理艾美捷科技产品,具体的蛋白序列可查看提供的英文版本产品说明书。
来源宿主
提供的Human CellExp™CD33 / SIGLEC-3,Fc标签,人类重组Human CellExp™ CD33 / SIGLEC-3, Fc Tag, Human Recombinant
产品来源宿主,查看该产品说明书,或者在线咨询我们。
溶解建议
Reconstitute in sterile deionized water to a concentration of 50 μg/ml.