Human CellExp™ Her2 / ErbB2, Fc Tag, Human Recombinant
供应商
Biovision
产品货号
P1346-10
产品报价
¥已停产
产品说明书
购买方式
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产品新闻
背景资料
Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2, HER-2, HER-2 /neu, NEU, NGL, TKR1 and c-erb B2, and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. Approximately 30% of breast cancers have an amplification of the HER2 gene or overexpression of its protein product. Overexpression of this receptor in breast cancer is associated with increased disease recurrence and worse prognosis. HER2 appears to play roles in development, cancer, communication at the neuromuscular junction and regulation of cell growth and differentiation.
序列
提供的Human CellExp™Her2 / ErbB2,Fc标签,人类重组Human CellExp™ Her2 / ErbB2, Fc Tag, Human Recombinant是Biovision品牌中国区域总代理艾美捷科技产品,具体的蛋白序列可查看提供的英文版本产品说明书。
来源宿主
提供的Human CellExp™Her2 / ErbB2,Fc标签,人类重组Human CellExp™ Her2 / ErbB2, Fc Tag, Human Recombinant产品来源宿主,查看该产品说明书,或者在线咨询我们。
溶解建议
Reconstitute in sterile deionized water to a concentration of 50 μg/ml.