Recombinant Human Mitogen-Activated Protein Kinase-Activated Protein Kinase 3
供应商
ProSpec
产品货号
PKA-045
产品报价
¥询价/1mg ¥20ug ¥5ug
产品说明书
购买方式
在线支付宝及网银支付、支票、现金、电汇,或拨打全国免费服务电话4006800868与我们联系.
产品新闻
背景资料
MAP kinase-activated protein kinase 3 (MAPKAPK3) is involved in inflammatory Reaction by regulating tumor necrosis factor (TNF) and IL6 production post-transcriptionally. MAPKAPK3 phosphorylates AU-rich elements (AREs)-binding proteins, like TTP/ZFP36, leading to control of stability and translation of TNF and IL6 mRNAs. Phosphorylation of TTP/ZFP36 (a major post-transcriptional regulator of TNF), promotes its binding to 14-3-3 proteins and reduces its ARE mRNA affinity resulting in inhibition of dependent degradation of ARE-containing transcript. MAPKAPK3 is activated by growth inducers and stress stimulation of cells.
序列
请咨询我们客服或者请查看品牌官方网站
来源宿主
大肠杆菌中重组表达.
溶解建议
提供的重组人促分裂素原活化蛋白激酶激活的蛋白激酶3产品形式为无菌的无色溶液.
保存建议
建议将重组人促分裂素原活化蛋白激酶激活的蛋白激酶3产品整瓶保存于4℃可保存2-4周. 长期保存,请置于-20℃.长期保存,推荐添加载体蛋白 (0.1% HSA or BSA).请避免反复冻融.