Recombinant Human Low Density Lipoprotein Receptor Adaptor Protein 1
供应商
ProSpec
产品货号
PRO-1033
产品报价
¥询价/1mg ¥20ug ¥5ug
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产品新闻
背景资料
LDLRAP1 is a cytosolic protein that holds a phosphotyrosine binding (PTD) domain and performing as a cytosolic adaptor it couples LDLR to endocytic machinery. Mutations in LDLRAP1 are the reason for autosomal recessive hypercholesterolemia (ARH) which is a condition triggered by defective internalization of LDL receptors (LDLR) in the liver.