Recombinant Human Regulator of G-Protein Signaling 1
供应商
ProSpec
产品货号
PRO-1118
产品报价
¥询价/1mg ¥20ug ¥5ug
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产品新闻
背景资料
RGS1 belongs to the regulator of G-protein signaling family. The RGS1 protein is situated on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif termed the RGS domain. RGS1 diminish s the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and performing as a GTPase activating protein (GAP), boosting the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, creating inactive G-protein heterotrimers, thus terminating the signal.