Recombinant Human TGFB1-Induced Anti-Apoptotic Factor 1
供应商
ProSpec
产品货号
PRO-1211
产品报价
¥询价/10ug ¥1mg ¥2ug
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产品新闻
背景资料
TGFB1-induced anti-apoptotic factor 1 (TIAF1) hinders the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. The TIAF1 protein is involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation. TIAF1 is not detected in normal kidney and liver. TIAF1 is up-regulated in chronic and acute allograft rejection: expressed in the inflammatory infiltrate and in tubular epithelial cells.