Recombinant Human Actin, Alpha 2, Smooth Muscle, Aorta
供应商
ProSpec
产品货号
PRO-1220
产品报价
¥询价/10ug ¥1mg ¥2ug
产品说明书
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产品新闻
背景资料
ACTA2 is a member of the actin family of proteins, an extremely conserved family of proteins which takes part in cell motility, structure and integrity. Three types of actin isoforms are known: Alpha, beta and gamma. Alpha actins are a main factor of the contractile mechanism, and beta and gamma take part in the regulation of cell motility. ACTA2 is an alpha actin which is located in skeletal muscle. Mutations in ACTA2 cause aortic aneurysm familial thoracic type 6. Various alternatively spliced variants, encoding the same protein were identified.