Recombinant Human SPRY Domain-Containing SOCS Cox Protein 2
供应商
ProSpec
产品货号
PRO-1264
产品报价
¥询价/1mg ¥20ug ¥5ug
产品说明书
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产品新闻
背景资料
SPRY Domain-Containing SOCS Cox Protein 2 (SPSB2) belongs to a suppressor of cytokine signaling (SOCS) family, and is a member of the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. SPSB2 is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. SPSB2 is apparent substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and ensuing proteasomal degradation of target proteins.