Recombinant Human Microfibrillar-associated Protein 2
供应商
ProSpec
产品货号
PRO-1265
产品报价
¥询价/10ug ¥1mg ¥2ug
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产品新闻
背景资料
Microfibrillar-associated protein 2 (MFAP2) is an O-glycosylated protein discharged to the extracellular space and the extracellular matrix. MFAP2 connects with biglycan and elastin in a ternary complex. MFAP2 plays a key role in the support and distensibility of the juxtacanalicular region of these collector channels. MFAP2 inhibits LTB-1 binding to fibrillin-1, promotes the phosphorylation of Smad2 thus mediating the consequent extracellular deposition of latent TGFbeta.