Recombinant Human Par-6 Partitioning Defective 6 Homolog Beta
供应商
ProSpec
产品货号
PRO-1307
产品报价
¥询价/100ug ¥10ug ¥2ug
产品说明书
购买方式
在线支付宝及网银支付、支票、现金、电汇,或拨打全国免费服务电话4006800868与我们联系.
产品新闻
背景资料
Partitioning defective 6 homolog beta (PARD6B) belongs to the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. Cellular asymmetry is crucial for the development of multicellular organisms. PARD (partitioning-defective) proteins have central roles in asymmetric cell division and polarized growth, whereas Cdc42 and Rac mediate establishment of cell growth and polarity and contribute to oncogenic transformation by Ras. PARD6B is expressed in pancreas and in both the adult and the fetal kidney, and is weakly expressed in the placenta and the lung.