Recombinant Human Death Effector Domain Containing
供应商
ProSpec
产品货号
PRO-1349
产品报价
¥询价/10ug ¥1mg ¥2ug
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产品新闻
背景资料
Death effector domain-containing protein (DEDD) is a cytoplasmic protein. The cell death activity of DEDD relates to its nuclear localization. DEDD translocates to the nucleus during CD95-mediated apoptosis, there it localizes to nucleoli-like structures, activates caspase-6 and particularly inhibits RNA polymerase I-dependent transcription. DEDD is usually expressed in a variety of tissues, and found in the highest levels in the testis. Overexpression of DEDD was shown to induce weak apoptosis.