Recombinant Human Lipopolysaccharide-Induced TNF Factor
供应商
ProSpec
产品货号
PRO-1350
产品报价
¥询价/1mg ¥20ug ¥5ug
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产品新闻
背景资料
Lipopolysaccharide-induced TNF-alpha factor (LITAF) is a small integral membrane protein of lysosome/late endosome. The expression of inflammatory cytokines such as TNF-alpha in Lipopolysaccharide-induced processes is mediated by LITAF. LITAF connects to STAT6B, which belongs to the STAT6 family forming a complex on the TNF-alpha promoter that modifies TNF activity. High levels of expression of LITAF mRNA are observed mostly in the placenta, peripheral blood leukocytes, lymph nodes and spleen.