Recombinant Human Major Histocompatibility Complex Class II DO Alpha
供应商
ProSpec
产品货号
PRO-1535
产品报价
¥询价/1mg ¥20ug ¥5ug
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产品新闻
背景资料
Major Histocompatibility Complex Class II DO Alpha (HLA-DOA) is a significant modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. HLA-DOA forms a heterodimer along with HLA-DOB. The heterodimer is located in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. HLA-DOA exhibits very little sequence variation, particularly at the protein level.