Recombinant Human nudE Nuclear Distribution Gene E Homolog 1
供应商
ProSpec
产品货号
PRO-204
产品报价
¥询价/1mg ¥20ug ¥5ug
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产品新闻
背景资料
NDE1 is a cytoplasmic protein which is a member of the nudE protein family. Phosphorylated during mitosis, NDE1 is critical for the formation and function of the mitotic spindle in M phase and functions to regulate the Dynein-mediated transport of kinetochore proteins, as well as centrosome duplication during interphase. NDE1 is believed to interact with NDEL1, LIS1 and Dynein IC1/2, cytosolic in a signaling pathway which regulates the formation of neurons and is fundamental to the development of the cerebral cortex.