Recombinant Human V-crk Sarcoma Virus CT10 Oncogene
供应商
ProSpec
产品货号
PRO-275
产品报价
¥询价/1ug ¥50ug ¥5ug
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产品新闻
背景资料
CRK belongs to the signaling adapter protein family which binds to several tyrosine-phosphorylated proteins. CRK is involved in many cellular processes such as apoptosis, proliferation, and differentiation. CRK has a modular domain architecture consisting of an SH2 followed by two SH3 domains (src-homology domains). The N-terminal SH2 domain of the CRK protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.