Recombinant Human Mothers Against Decapentaplegic Homolog 4
供应商
ProSpec
产品货号
PRO-459
产品报价
¥询价/10ug ¥1mg ¥50ug
产品说明书
购买方式
在线支付宝及网银支付、支票、现金、电汇,或拨打全国免费服务电话4006800868与我们联系.
产品新闻
背景资料
SMAD4 is part of the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD4 promotes the binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides the function of activation required for SMAD1 or SMAD2 to stimulate transcription acts as a tumor suppressor. SMAD4 is a target molecule for functional inactivation in cervical cancer. SMAD4 is an important biomarker for malignant transformation atakes part in inducing apoptosis by modulating Bcl-2/Bax balance.
序列
请咨询我们客服或者请查看品牌官方网站
来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered colorless solution. The SMAD4 protein solution contains 20mM Tris-HCl pH-8, and 20% glycerol.
保存建议
SMAD4 although stable 4℃ for 4 weeks, should be stored desiccated below -18℃.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.