Recombinant Human Down-Regulator of Transcription 1
供应商
ProSpec
产品货号
PRO-542
产品报价
¥询价/1mg ¥25ug ¥5ug
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产品新闻
背景资料
DR1 is a phosphoprotein that inhibits both basal and activated levels of transcription. DR1 is phosphorylated in vivo which affects its interaction with TBP. DR1 has a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. By selectively repressing polymerases II and III, DR1 alters the physiological balance of transcriptional output in favor of polymerase I.