中文名称

【Bcl-XL GST】重组人B细胞淋巴瘤因子2 XL，GST标签

英文名字

Recombinant Human B-Cell Leukemia/Lymphoma XL GST Tag

供应商

ProSpec

产品货号

PRO-640

产品报价

￥询价/10ug   ￥1mg   ￥2ug

产品说明书

购买方式

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产品新闻

背景资料

Bcl-XL is a transmembrane protein located in the mitochondrial membranes of cells that are long-lived and postmitotic， such as adult brain cells. It plays arole in the signal transduction pathway of the FAS-Ligand. Bcl-XL is an anti-apoptotic protein which is a member of the Bcl-2 family which are able to form heterodimers， and this is an significant event in the regulation of apoptosis. BCL-XL is involved in the survival of cancer cells.
Bcl-xL is the leading monitor of apoptosis/active cell suicide. Bcl-xL has cell death repressor activity and therefore acts as a survival protein.

序列

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来源宿主

大肠杆菌中重组表达

溶解建议

Sterile Filtered White lyophilized （freeze-dried） powder. The protein contains 10mM Tris-HCL pH-8， 1mM EDTA and 250mM NaCl. Suspend BclXL in 100?l of 0.5M Acetic acid， over night at 4°C. Dilute 10 fold into selected buffer system. Bcl-XL has tendency to form intramolecular disulfide bond， 5mM DTT is recommended in assay buffer. When running SDS-PAGE gel， 10mM DTT is recommended.

保存建议

Lyophilized Bcl-XL although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution Bcl-XL should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.

其他

ProSpec 是一家全球著名细胞因子蛋白生产和研发的公司，具有20多年的生产经验，专注于蛋白（重组及合成）生产研发。我们的核心产品包括：干扰素、白介素、骨蛋白、肿瘤坏死因子、成纤维生长因子、瘦素、干细胞因子、催乳素、表皮生长因子、胰岛素样生长因子、神经生长因子、集落刺激因子、激素、酶、病毒抗原以及各种重组蛋白等。 领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。

注意

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