Recombinant Human Cbp/p300-Interacting Transactivator 2
供应商
ProSpec
产品货号
PRO-701
产品报价
¥询价/1mg ¥20ug ¥5ug
产品说明书
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产品新闻
背景资料
CITED2 is a significant transcriptional cofactor that takes part in multiple organ development. CITED2 is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator and a negative regulator for HIF1A through its competitive binding with HIF1A to CBP/p300. CITED2 is essential for mouse fetal liver hematopoiesis and is necessary for the appropriate formation of the hyaloid vasculature and for lens morphogenesis. CITED2 is a coactivator of HNF4alpha and necessary for liver development. CITED2 is a coactivator of PPAR-alpha and both participate in signaling cascades of hypoxic response and angiogenesis.
序列
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered colorless solution. The CITED2 solution contains 20mM Tris pH-8, 1mM DTT ,0.1M NaCl & 50% glycerol.
保存建议
CITED2 although stable 4℃ for 4 weeks, should be stored desiccated below -18℃. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.