Recombinant Human MAD2 Mitotic Arrest Deficient-Like 1
供应商
ProSpec
产品货号
PRO-934
产品报价
¥询价/1ug ¥50ug ¥5ug
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产品新闻
背景资料
MAD2L1-binding protein (MAD2L1) is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is vital for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.