The WNT gene family consists of structurally related genesnwhich encode secreted signaling proteins. These proteins have beennimplicated in oncogenesis and in several developmental processes,nincluding regulation of cell fate and patterning duringnembryogenesis. This gene is a member of the WNT gene family. Itnencodes a protein which shows 98%, 98% and 87% amino acid identitynto the mouse, rat and the xenopus Wnt5A protein, respectively. Thenexperiments performed in Xenopus laevis embryos identified thatnhuman frizzled-5 (hFz5) is the receptor for the Wnt5A ligand andnthe Wnt5A/hFz5 signaling mediates axis induction. [provided bynRefSeq].
应用类型
WB, IHC-P, Flow
免疫原
This WNT5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 amino acids from the Central region of human WNT5A.
来源宿主
兔
反应性
人, 小鼠, 大鼠
保存建议
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.