ARHGEF3 抗体-ARHGEF3 Antibody代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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一抗

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背景资料: Rho-like GTPases are involved in a variety of cellularnprocesses, and they are activated by binding GTP and inactivated bynconversion of GTP to GDP by their intrinsic GTPase activity.nGuanine nucleotide exchange factors (GEFs) accelerate the GTPasenactivity of Rho GTPases by catalyzing their release of bound GDP.nThis gene encodes a guanine nucleotide exchange factor, whichnspecifically activates two members of the Rho GTPase family: RHOAnand RHOB, both of which have a role in bone cell biology. It hasnbeen identified that genetic variation in this gene plays a role innthe determination of bone mineral density (BMD), indicating thenimplication of this gene in postmenopausal osteoporosis.nAlternatively spliced transcript variants encoding differentnisoforms have been found for this gene.

免疫原: This ARHGEF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-240 amino acids from the Central region of human ARHGEF3.

保存建议: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

其他: ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。