FUNCTION: Positive-acting transcription factor that binds to the immunoglobulin enchancer MUE3 motif. It binds also very well to a USF/MLTF site. Binding of TFE3 to DNA induces DNA binding.
DISEASE: Chromosomal aberrations involving TFE3 may be a cause of papillary renal cell carcinoma (PRCC). Translocation t(X;1)(p11.2;q21.2) with PRCC; translocation t(X;1)(p11.2;p34) with PSF; inversion inv(X)(p11.2;q12) that fuses NONO to TFE3.
应用类型
WB
免疫原
432-541
来源宿主
鸡
反应性
人, 小鼠, 大鼠
保存建议
TFE3 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.