FUNCTION: SAM (substrate-adhesion molecule) that appears to inhibit cell migration. May play a role in supporting the growth of epithelial tumors. Is a ligand for integrins α-8/β-1, α-9/β-1, α-V/β-3 and α-V/β-6.
SUBUNIT: Hexameric. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4.
应用类型
WB
免疫原
18-175
来源宿主
鸡
反应性
人
保存建议
TNC antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.