FUNCTION: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB.
CATALYTIC ACTIVITY: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
SUBUNIT: In contrast to PTP4A1 and PTP4A3, does not interact with tubulin. Interacts with RABGGTB.
应用类型
WB
免疫原
1-33
来源宿主
鸡
反应性
人, 小鼠, 大鼠
保存建议
PTP4A2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.