FUNCTION: Activates NF-κ-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
SUBUNIT: CARD14 and BCL10 bind to each other by CARD-CARD interaction.
SIMILARITY: Contains 1 PDZ (DHR) domain.
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Expressed in placenta. Also detected in HeLa S3 cells, but not in the other cancer cell lines tested.
应用类型
WB
免疫原
221-330
来源宿主
鸡
反应性
人
保存建议
CARD14 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.