FUNCTION: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
SUBUNIT: Heterodimer of an α and a β subunit.
SIMILARITY: Belongs to the TFIIF β subunit family.
SUBCELLULAR LOCATION: Nuclear.
应用类型
WB
免疫原
1-249
来源宿主
鸡
反应性
人, 小鼠, 大鼠
保存建议
GTF2F2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.