DISEASE: Chromosomal aberrations activating TCL1A are found in chronic T-cell leukemias (T-CLL). Translocation t(14;14)(q11;q32); translocation t(7;14)(q35;q32); inversion inv(14)(q11;q32) that involves the T-cell receptor α/Δ locuses.
SUBUNIT: Homodimer.
SIMILARITY: Belongs to the TCL1 family.
SUBCELLULAR LOCATION: Microsomal fraction.
TISSUE SPECIFICITY: Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation.
应用类型
WB
免疫原
1-114
来源宿主
鸡
反应性
人
保存建议
TCL1A antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.