FUNCTION: Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.
SUBUNIT: Adapter protein complex 3 (AP-3) is an heterotetramer composed of two large adaptins (Δ/AP3D1 and β3A/AP3B2 or β3B/AP3B1), a medium adaptin (mu3A/AP3M1 or mu3B/AP3M2) and a small adaptin (Σ3A/AP3S1 or Σ3B/AP3S2). Interacts with CENTG2 (By similarity).
应用类型
WB
免疫原
1-193
来源宿主
鸡
反应性
人, 小鼠
保存建议
AP3S2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.