FUNCTION: Binds to the 5'stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a comformational change upon RNA-binding.
SUBUNIT: Interacts with RAD17.
SIMILARITY: Belongs to the ribosomal protein L7Ae family.
SUBCELLULAR LOCATION: Nuclear; nucleolar. Concentrated in the dense fibrillar component of the nucleolus.
应用类型
WB
免疫原
1-128
来源宿主
鸡
反应性
人, 大鼠
保存建议
NHP2L1 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.