FUNCTION: Rev appears to act post-transcriptionally to relieve negative repression of Gag and Env production.
PTM: Phosphoprotein whose state of phosphorylation is mediated by a specific serine kinase activity present in the nucleus. Phosphorylated at separate regions by protein kinase CK2 and MAPK. Phosphorylation by CK2 could play a role in Rev down-regulation.
SUBCELLULAR LOCATION: Nuclear; accumulates in the nucleoli.
应用类型
WB
免疫原
1-116
来源宿主
鸡
反应性
Virus
保存建议
HIV-Rev antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.