中文名称

MLN4924

英文名字

MLN4924

供应商

Viva Bioscience

产品货号

VB2238-1

产品报价

￥1750/1mg

产品说明书

购买方式

产品新闻

背景资料

MLN-4924 is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival. NAE activates Nedd8 (Neural precursor cell expressed, developmentally down-regulated 8), an ubiquitin-like (UBL) protein that modifies cellular targets in a pathway that is parallel to but distinct from the ubiquitin-proteasome pathway (UPP). Functioning in diverse regulatory activities, proteins conjugated to UBLs like Nedd8 typically are not targeted for proteasomal degradation.

产品描述

Cell permeable substrate-assisted inhibitor of the NEDD8 E1 activating enzyme

产品形式

保存建议

其他

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注意

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