LAT Antibody is a Rabbit Polyclonal antibody against LAT. The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
应用类型
WB
免疫原
LAT
来源宿主
兔
反应性
人
保存建议
建议收到该Linker For Activation Of T-Cell (LAT) Antibody产品后,储存温度为-20°C。避免重复冻融