CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
应用类型
WB, IHC
免疫原
CDC23
来源宿主
兔
反应性
人
保存建议
建议收到该Cell Division Cycle Protein 23 (CDC23) Antibody产品后,储存温度为-20°C。避免重复冻融