NANOG Antibody is a Mouse against Human. NANOG is a multidomain homeobox transcription factor which functions to maintain the undifferentiated state of pluripotent stem cells. NANOG expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.
应用类型
ELISA, WB, IHC
免疫原
Homeobox Protein NANOG (NANOG)
来源宿主
小鼠
反应性
人
保存建议
建议收到该Homeobox Protein NANOG (NANOG) Antibody产品后,储存温度为-20°C。避免重复冻融