Human 26S Proteasome Non-ATPase Regulatory Subunit 9 (PSMD9) Protein
英文名字
Human 26S Proteasome Non-ATPase Regulatory Subunit 9 (PSMD9) Protein
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Abbexa
产品货号
abx167135
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¥询价/10ug ¥询价/50ug ¥询价/100ug ¥询价/200ug ¥询价/1mg
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背景资料
Proteasome 26S Subunit, Non ATPase 9 Protein is a recombinant Human protein expressed in E. coli. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene.